20 May 2000

CNTF Therapy In Primates/Human Trials
Adapted from:Hum Gene Ther 2000 May 20;11(8):1177-87; Mittoux V,et al

Phase I clinical trials in HD patients have now been initiated using CNTF as a neurotrophic/ neuroprotective agent and the macroencapsulation technique as a gene delivery system...

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11 Aug 2000

CNTF Trial Method
Hum Gene Ther 2000 Aug;11(12):1723-1729, Bachoud-Levi A., et al. INSERM U421, Faculte de Medecine, 94010 Creteil, France and Service de Neurologie, Hopital Henri Mondor, 94010 Creteil, France

A device, containing up to 106 human CNTF-producing BHK cells surrounded by a semipermeable membrane, will be implanted into the right lateral ventricle of 6 patients...

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