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A review of the treatment options for HD symptoms

HD Lighthouse Contributing Editor's Comment: The Expert Opinion on Pharmacotherapy journal has graciously given us permission to reprint the Bonelli and Hofmann review of medication for Huntington's Disease. Their website is here: http://www.ingentaconnect.com/content/apl/eop

Because HD is a rare disease, many physicians will be unfamiliar with the medications currently used to treat its symptoms. You may want to print the review for your doctor.

-- Marsha L. Miller, Ph.D.
Posted to the HDL: 19 May 2006



A review of the Treatment Options for Huntington's Disease

Raphael M Bonelli, Peter Hofmann

At the present time the only treatment options available in HD are for the symptoms of HD. There are several substances available today for the treatment of chorea and based on data from open-label studies or even case reports, the authors of the attached article recommend riluzole and olanzapine for the treatment of chorea caused by HD. They also recommend SSRIs and mirtazapine for the treatment of depression, and atypical antipsychotic drugs for HD psychosis and behavioral problems. The authors recommend that psychotherapy, physiotherapy, and speech therapy be part of the treatment program where appropriate.

The entire journal article is available as a PDF download by clicking on download journal article. If you do not have an Adobe© reader you should first download the Adobe reader.

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Source: Expert Opinion on Pharmacotherapy. April 2004, Vol. 5, No. 4, Pages 767-776

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