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  HD Lighthouse Editors Comment: The loss of BDNF caused by the mutant HD gene can be compensated for by physical fitness. The magnitude of the effect is very large. --Jerry

Posted to HDLighthouse: 22-Feb-02
HDL Update: BDNF

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What can I currently do to improve my short/long term memory?
No "real" therapy (drug or behavioral) yet exists. Emerging literature, primarily from cognitive psychologists however, suggests that "brain exercise" may work to maintain optimal functioning of working (one type of short-term) memory.

More generally, recent research suggests one MOST IMPORTANT thing you can do to maintain cognitive vitality as you age - exercise (!)

Physical exercise works to promote cognitive health in two ways.

First, cardiovascular fitness (low cholesterol and less artherosclerosis) minimizes the chances of "mini-strokes." Modern brain imaging studies have revealed a high incidence of these clinically undiagnosed events. Presumably, they cause small but cumulative damage to the brain, which eventually results in memory loss.

Second, physical exercise actually produces increases in a brain chemical called, BDNF. BDNF promotes neuronal survival and may protect against the damaging effects (cell death) of stress. Combined, these positive effects of physical exercise are 40 times more important for cognitive health than any other known factor.

Source: From Tim Tulley, Science Hot Line, PBS Site

Read the HDAC/HDLighthouse Forum. Post your comments
   
 
Exercise Extends Life
The following study confirms that a simple change in lifestyle can be profoundly beneficial. Exercise may be more important than CAG count and all other risk factors, except for age, in determining how well and long we live...
The Associated Press
Posted to HDL: 14 Mar 2002

Tai Chi Defence
Sometimes not believing your neurologist can be a lifesaver. The simple truth is that exercise, diet and spirit can have a profound effect on the quality of everyones life. Ross Monson has found his path to enlightenment....
Edmonton Journal, Scott McKeen, Journal Staff Writer
Posted to HDL: 02 Mar 2002

BDNF
What can I currently do to improve my short/long term memory?....
From Tim Tulley, Science Hot Line, PBS Site
Posted to HDL: 22 Feb 2002

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