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HomeTreatment & CareCareExercise \ Updates
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HD Lighthouse Editors Comment: The loss
of BDNF caused by the mutant HD gene can be compensated for by physical
fitness. The magnitude of the effect is very large. --Jerry
Posted to HDLighthouse: 22-Feb-02
More generally, recent research suggests one MOST IMPORTANT thing you can do to maintain cognitive vitality as you age - exercise (!) Physical exercise works to promote cognitive health in two ways. First, cardiovascular fitness (low cholesterol and less artherosclerosis) minimizes the chances of "mini-strokes." Modern brain imaging studies have revealed a high incidence of these clinically undiagnosed events. Presumably, they cause small but cumulative damage to the brain, which eventually results in memory loss. Second, physical exercise actually produces increases in a brain chemical called, BDNF. BDNF promotes neuronal survival and may protect against the damaging effects (cell death) of stress. Combined, these positive effects of physical exercise are 40 times more important for cognitive health than any other known factor. Source: From Tim Tulley, Science Hot Line, PBS Site
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