Therapeutic Trials in Progress

CARE-HD (Coenzyme Q10 and Remacemide Evaluation in HD) is a multi-center clinical trial under the direction of Karl Kieburtz, M.D. at the University of Rochester, and Walter Koroshetz, M.D. at Massachusetts General Hospital. This study is evaluating the naturally occurring substance CoQ10 and the drug Remacemide as potential therapies to slow or stop the progression of HD. The trial was fully enrolled in record time and is now one third of the way through completion. All 347 subjects will be followed for 2 1/2 years, with results of the trial expected in 2001. Other therapeutic trials are under development.