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  HD Lighthouse Editors Comment: The following small study suggests that HD patients have more mental problems than those with other brain conditions. The study also suggests that a surprisingly large percentage of neurologically healthy folks, including the researchers, have the same problems. -- Jerry

Posted to HDLighthouse: 03Aug02
HDL Update: A Comparison to Huntington's Disease

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Psychopathology
HD Researchers Christopher Ross and group compaired HD patients to others. Here is what they found. Compaired to neurologicaly healthy subjects, HD patients have:
  • less than twice the incidence of non-cognitive disorders.
  • about three times the incident of mood disorders.
OBJECTIVE:

This study estimated the psychiatric morbidity of patients with degenerative cerebellar diseases.
METHOD: The study included a series of 31 patients with degenerative cerebellar diseases, compared with 21 patients with Huntington's disease and 29 neurologically healthy comparison subjects. Comprehensive psychiatric evaluations, including the Structured Clinical Interview for DSM-IV and psychopathology rating scales, were administered.
  % noncognitive psychiatric disorders mood disorders personality change

Source: Psychopathology in Patients With Degenerative Cerebellar Diseases: A Comparison to Huntington's Disease. Am J Psychiatry. 2002 Aug;159(8):1306-14. Leroi I, et al.

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