New to the Huntington's Disease Lighthouse?
 Welcome to the HDlighthouse!
 Getting started.
 
TreatmentNow \ Creatine
 
Creatine
  Creatine This section is devoted to what we currently know about creatine and what role creatine may play in the battle against Huntington's Disease.

You probably know of creatine as a supplement for muscle builders. But creatine has also been shown to have some interesting properties that have HD researchers excited. Read on for more details.

 

Creatine is a compound which has been found to slow disease progression and increase survival time in the R6/2 mouse model of HD. It has been found to be safe and well tolerated in Huntington's patients and is currently in clinical trials. Creatine addresses two sources of pathology in Huntington's Disease. Mitochondrial dysfunction results in energy impairment; creatine boosts cellular energy. In addition, oxidative stress occurs with aging and neurodegenerative disorders including Huntington's; creatine is an antioxidant.

For information about creatine from the Huntington Project review here: http://www.huntingtonproject.org/Portals/0/creatine.pdf

Read the HDAC/HDLighthouse Forum. Post your comments
   
 

Considering creatine as part of your proactive battle?
Read Dr. Goodman's:
Approach to potential treatments.
Pamphlet on Creatine.

5 Jul 2009
Creatine and CoQ10
Creatine and CoQ10 have additive effects in the R6/2 mice
 
16 Jan 2007
Creatine trials
Avicena is planning a phase II toxicology trial for its creatine product followed soon by a phase III trial.
 
1 Aug 2006
A Better CoQ10 for Huntington's Disease Coming Soon?
CHDI has contracted with Edison Pharmaceuticals to develop a variation of COQ10 that will be much more effective for those with HD.
 
4 Jun 2006
CoQ-10: More is Best
Higher doses of CoQ10 extend the lives of the HD mice even further.
 
29 May 2006
Blueberries restore age related decline in HSP 70
There's a new reason to add blueberries to your diet - it restores the cell's ability to generate the heat shock protein 70 which normally declines with aging.
 
28 Apr 2006
Trehalose: Sweet Rescue
A review of research with trehalose shows that it has potential for both prevention and treatment of neurodegenerative diseases. ...
 
24 Mar 2006
A Perspective for Treating HD Today
Jim Tretheway, a leading advocate for HD patients offers some valuable insight into what can be done today to fight Huntington's Disease. ...
 
30 Jan 2006
More evidence for creatine
A well done new study of creatine shows that it is safe, tolerable, and reduces a biomarker of DNA oxidative injury. ...
 
19 Dec 2005
More on SSRIs and BDNF
More research on the beneficial affects of SSRI antidepressants. ...
 
1 Dec 2005
NEUROSCIENCE and NINDS 2005 - An Advocate Perspective
...
 

All Updates for Treatment Now

Disclaimer & Privacy Policy | Welcome | Site Feedback Marsha@HDLighthouse.org